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Drug Metab Dispos 33 , 649656, doi: dmd.104.002964 [pii]10.1124/dmd.104.002964 (2005)

274,275 Interestingly, relatively low levels of Cu have been measured in mutant SOD1 proteins, whereas increased levels of Cu have been reported in the cerebrospinal fluid of patients with ALS and mouse models of ALS